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2′-Oxo-PCE (also known as as Eticyclidone, and O-PCE) is a lesser-known novel dissociative substance of the arylcyclohexylamine class that produces dissociative, anesthetic, stimulating and hallucinogenic effects when administered. It is structurally related to arylcyclohexylamines like MXE, 3-MeO-PCE, and deschloroketamine and is speculated to produce its effects through its activity as an NMDA receptor antagonist.

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Chemistry of 2′-Oxo-PCE

O-PCE, or 2′-Oxo-PCE, belongs to the arylcyclohexylamine chemical class. Arylcyclohexylamine drugs are named for their structures which include a cyclohexane ring bound to an aromatic ring along with an amine group. Deschloroketamine contains a phenyl ring bonded to a cyclohexane ring substituted with an oxo group (cyclohexanone) at R1. Bound to the adjacent alpha carbon (R2) of the cyclohexanone ring is an amino ethyl chain -NCH2CH3. 2′-Oxo-PCE, like MXE contains an amino ethyl chain rather than the amino methyl chain found in DCK and ketamine. 2′-Oxo-PCE is homologous to DCK, differing only in the length of their carbon chain.

The structural similarities O-PCE shares with DCK, which has been speculated to have antibacterial properties, has raised some concern as to whether it also shares these properties as well. However, due to the lack of scientific research on the subject, whether this is true currently remains entirely unknown. It is advised that users of this substance should keep in mind that the possibility of prolonged use may pose a serious threat to one’s health and immune system if this does prove to be the case.

Effects 2′-Oxo-PCE

In comparison to DCK, ketamine and MXE, this compound can be described as generally more stimulating with fewer cognitive and sensory suppressions. The first half of its duration has been reported to produce primarily stimulating effects with minimal dissociation whilst the second half is primarily dissociating with minimal stimulation.

O-PCE has been reported to produce more physical side effects than other dissociatives such as MXE, ketamine, and 3-MeO-PCP. Its side effects are comparable to diphenidine, MXP, and ephenidine.

  • Stimulation – This substance is extremely stimulating when compared to other dissociatives such as ketamine, MXE, or DCK. Its stimulation can be compared to classical stimulants such as methylphenidate or cocaine, but significantly less functional and more inebriating.
  • Dizziness
  • Increased heart rate – This substance has been reported to cause more physical side effects than MXE, ketamine, and 3-MeO-PCP such as increased heart rate.

What is 2′-OXO-PCE used for?

Deschloroketamine (DXE, DCK, 2′-OxoPCM) is a dissociative anesthetic that has been sold online as a designer drug. It has also been proposed for the treatment of bacterial, fungal, viral or protozoal infections and for immunomodulation at doses of 2 mg per day.

Additional information

Product Weight

25g, 50g, 100g