Description

Buy 4-Aco-DMT (O-Acetylpsilocin) Online

4-Acetoxy-N,N-dimethyltryptamine (also known as 4-AcO-DMT, 4-Acetoxy-DMT, O-Acetylpsilocin, and psilacetin) is a novel psychedelic substance of the tryptamine class. 4-AcO-DMT is chemically similar to psilocybin, the active ingredient in psilocybin mushrooms (magic mushrooms). It belongs to a group known as the substituted tryptamines which act by stimulating serotonin receptors in the brain.

The synthesis of 4-AcO-DMT was first reported in 1963 by Albert Hofmann and Franz Troxler. However, its properties were not examined and no further studies were carried out. A 1999 paper by David E. Nichols suggested it as a useful alternative to psilocybin for pharmacological research. Reports of human use began to surface following its appearance on the online research chemical market in the 2010s.

Chemisty of 4-AcO-DMT

4-AcO-DMT, or 4-acetoxy-N,N-dimethyltryptamine, is a synthetic indole alkaloid molecule of the tryptamine chemical class. Tryptamines share a core structure comprising a bicylic indole heterocycle attached at R₃ to a terminal amino group via an ethyl side chain.

4-AcO-DMT is substituted at R₄ of its indole heterocycle with an acetoxy (-AcO) functional group CH₃COO−. It also contains two methyl groups CH₃– bound to the terminal amine R_N of the ethyl side chain.

What is 4-Aco-DMT (O-Acetylpsilocin) used for?

The psychedelic effects of 4-AcO-DMT are believed to come from its activity as a partial agonist for the 5-HT_2A receptor. However, the role of these interactions and how they result in the psychedelic experience is the subject of ongoing scientific investigation.

In the body, 4-AcO-DMT is suspected to be deacetylated into psilocin during first pass metabolism, by the acidic conditions in the stomach, and as it passes through the liver.

Effects of 4-Aco-DMT (O-Acetylpsilocin) .

Users frequently describe 4-AcO-DMT as being extremely similar to psilocybin mushrooms. It is generally described as euphoric, gentle, warm, and colorful. Visuals are reported by some users to be brighter and more neon in a manner reminiscent of DMT. It is also reported to be less nauseating than psilocybin mushrooms, which may be due to the fact that it does not require digesting mushroom matter.

• Sedation – 4-AcO-DMT is considered by most to be relaxing, stoning and mildly sedating. This sense of sedation is often accompanied by compulsive yawning.
• Perception of bodily heaviness
• Spontaneous bodily sensations – The general “body high” of 4-AcO-DMT can be described as a pleasurable, warm, soft and all-encompassing tingling sensation. This maintains a consistent presence that steadily rises with the onset and hits its limit once the peak has been reached. Once the peak of the experience or sensation is reached it can produce feelings of pronounced physical and cognitive euphoria along with tranquility, a sense of lethargy or sedation, or total immobilization depending on the dose.

Where can you buy 4-Aco-DMT (O-Acetylpsilocin) ?

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